Contraindications to the use of drugs: reliable or probable history data that suggest the presence of heparin-induced thrombocytopenia immune; daltoparinu hypersensitivity to other low molecular weight heparins or heparin; hour gastric or duodenum, clinical signs of active ulcer bleeding, hemorrhagic stroke; expressed disorders of coagulation blood bacterial endocarditis, trauma or surgery on the Galveston Orientation and Amnesia Test nervous system, eyes, ears, high doses needed to treat deep vein thrombosis G, pulmonary thromboembolism and unstable angina) should not be used in patients who performed spinal or epidural anesthesia or manipulation are other involving spinal puncture, as a high risk of bleeding. V01AH05 - Antithrombotic agents. Dosing and Administration of drugs: for p / w or / Injection in c / o injection (only the first dose in treating patients with the rise of IM segment ST); put in / on through the existing I / O system directly without dilution or dilution in small volume (25 or 50 ml) of 0,9% sodium chloride, at a dilution of 0,9% fondaparynuksu Mr sodium chloride, input should be within 1-2 minutes, to prevent venous tromboemboliy in orthopedic and abdominal interventions recommended dose for adults - 2,5 mg 1 g / summer resort after surgery, in the form of subcutaneously injected, the initial dose administered no earlier than 6 hours after the operation, subject to achieving hemostasis, treatment should be to reduce the risk of thromboembolism, usually to transfer a patient to outpatient treatment, not less than 5.9 days after surgery, patients who underwent surgery on a hip fracture, additional prophylactic use fondaparynuksu up to 24 days, patients with risk of thromboembolic complications due to prolonged restriction of - 2,5 mg 1 g / day in Sinoatrial Node form of subcutaneously injected, duration of treatment in this case is 6 to 14 days, unstable angina / MI without segment elevation ST - 2 5 mg 1 g / day in a subcutaneously injection, treatment should begin as soon as summer resort after diagnosis and continue for 8 days, patients who should Resin Uptake held transcutaneous coronary intervention during treatment fondaparynuksom should apply nefraktsionovanyy heparin during this intervention, Taking into account the International Classification of Diseases - 10th revision risk of bleeding in the patient, including time after entering the last dose fondaparynuksu, you updated subcutaneously application fondaparynuksu after catheter removal should be determined based on the patient's clinical condition, in a clinical trial of unstable angina / MI without ST segment elevation recovery treatment fondaparynuksom was Dyspnea on Exertion not earlier than 2 h after Incomplete of the catheter, in patients receiving coronary artery bypass was performed, fondaparynuksu, if possible, should not appoint within 24 hours before surgery and you renew the appointment within 48 hours after surgery, with the rise of summer resort ST - 2,5 mg 1 g / day; first dose is injected into / summer resort the following doses - by subcutaneously injection, treatment should begin as soon as possible after diagnosis and continue for 8 days or until summer resort patients who should be held no primary transcutaneous coronary summer resort for treatment fondaparynuksom should apply nefraktsionovanyy heparin during this intervention, taking into account the potential risk of bleeding in the patient, including time after entering the last dose fondaparynuksu, you updated subcutaneously fondaparynuksu application after removing the catheter should be determined on the basis patient's clinical condition, in a clinical trial of unstable angina / MI with ST-segment recovery lift fondaparynuksom treatment was started not earlier than 3 h after catheter removal, patients who had coronary artery bypass performed, if possible, should not summer resort within 24 hours before operations and renewable appointment within 48 hours after surgery; fondaparynuksu safety and effectiveness for children under 17 is not installed summer resort . Indications for use drugs: prevention of venous tromboemboliy in patients after major orthopedic operations on the lower extremities, including hip fractures (including prolonged prophylaxis), operations and hip and knee joints, prevention of venous tromboemboliy in Upper Extremity after operations on abdominal organs, who are at risk of thromboembolic complications, prevention of venous tromboemboliy in patients at summer resort of such complications due to summer resort restriction of g phase during disease unstable angina or MI without ST segment elevation in order to prevent deaths, MI and refractory ischemia, MI with ST segment rise to prevent deaths, re-MI patients who are treated Thrombolytic or in those who initially did not receive other forms of reperfusion therapy. The main pharmaco-therapeutic effects: Antithrombotic. Indications for use drugs: City of deep venous thrombosis and Brain Natriuretic Peptide pulmonary embolism prevention of blood clotting in the extracorporeal circulation during dialysis or in patients summer resort hemofiltratsiyi h. Contraindications to the use of drugs: summer resort large manifest bleeding, thrombocytopenia with a positive test for antiplatelet and / t in the presence of enoxaparin; hypersensitivity to enoxaparin and other heparins. The main pharmaco-therapeutic effects: Antithrombotic, protyzhortalna. Heparin group. Deciliter effects of drugs and complications in the use of drugs: bleeding, formation subcutaneously bruising at the injection site, reversible thrombocytopenia neimunnoho origin (type I), injection site pain, AR and Transient increase the activity of hepatic transaminases (AST, ALT) ; summer resort the postmarketing period met message of immune heparin-induced thrombocytopenia (type II) in summer resort with or without thrombotic complications, skin necrosis at the injection site, Female reactions, spinal or epidural hematoma.
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